Name:Alpha-Mangostin
Synonyms:N/A
CAS Number:6147-11-1
Formula:C24H26O6
M.w.:410.46
DMSO (mg/mL)Max Solubility:82
DMSO (mM)Max Solubility:199.78
Form:free base
SMILES:COC1=C(O)C=C2OC3=C(C(=C(CC=C(C)C)C(=C3)O)O)C(=O)C2=C1CC=C(C)C
ALogP:5.935
Target:Dehydrogenase,STING
Pathway:Metabolism
Information:Alpha-mangostin is the main xanthone purified from mangosteen and has health promoting benefits including anti-bacterial, anti-inflammatory, anti-oxidant, anti-cancer and cardioprotective activities. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM. Alpha-mangostin is also an agonist of human STING.
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