Name:Triglycidyl Isocyanurate (Teroxirone)
Synonyms:Tris(2,3-epoxypropyl) Isocyanurate, TGI, TGIC
CAS Number:2451-62-9
Formula:C12H15N3O6
M.w.:297.26
DMSO (mg/mL)Max Solubility:59
DMSO (mM)Max Solubility:198.48
Form:Free Base
SMILES:O=C1N(CC2CO2)C(=O)N(CC3CO3)C(=O)N1CC4CO4
ALogP:-0.894
Target:DNA/RNA Synthesis,p53
Pathway:Apoptosis
Information:Triglycidyl Isocyanurate (Teroxirone, Tris(2,3-epoxypropyl) Isocyanurate, TGI, TGIC) is a triazene triepoxide with antineoplastic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl Isocyanurate alkylates and cross-links DNA, thereby inhibiting DNA replication. Triglycidyl Isocyanurate is also used in various polyester powder coatings in the metal finishing industry.
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