Name:CarboxyaMidotriazole orotate
Synonyms:L-651582 Orotate, CAI Orotate
CAS Number:187739-60-2
Formula:C22H16Cl3N7O6
M.w.:580.76
DMSO (mg/mL)Max Solubility:25
DMSO (mM)Max Solubility:43.05
Form:Orotate
SMILES:NC(=O)C1=C(N)[N](CC2=CC(=C(C(=C2)Cl)C(=O)C3=CC=C(Cl)C=C3)Cl)N=N1.OC(=O)C4=CC(=O)NC(=O)N4
ALogP:2.65
Target:Calcium Channel
Pathway:Transmembrane Transporters
Information:Carboxyamidotriazole Orotate (L-651582 Orotate) is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor. Carboxyamidotriazole Orotate is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate inhibits angiogenesis, tumor growth, invasion, and metastasis.
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