Name:Deferoxamine mesylate (Ba 33112)
Synonyms:Desferrioxamine B, DFOM, NSC 644468
CAS Number:138-14-7
Formula:C26H52N6O11S
M.w.:656.79
DMSO (mg/mL)Max Solubility:100
DMSO (mM)Max Solubility:152.26
Form:mesylate
SMILES:CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN.C[S](O)(=O)=O
ALogP:-1.304
Target:Autophagy,Beta Amyloid,Ferroptosis,HIF
Pathway:Autophagy
Information:Deferoxamine mesylate (Ba 33112, Desferrioxamine B, DFOM, NSC 644468) is the mesylate salt of Deferoxamine, which forms iron complexes and is used as a chelating agent. Deferoxamine is a ferroptosis inhibitor that stabilizes HIF-1α expression and improves HIF-1α transactivity in hypoxic and hyperglycemic states in vitro. Deferoxamine decreases beta-amyloid (Aβ) deposition and induces autophagy.Please do not prepare stock solutions with normal saline or PBS, as precipitation may occur.
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