Name:Madecassic acid
Synonyms:Brahmic acid
CAS Number:18449-41-7
Formula:C30H48O6
M.w.:504.7
DMSO (mg/mL)Max Solubility:100
DMSO (mM)Max Solubility:198.13
Form:Free Base
SMILES:CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5C(O)CC34C)C2C1C)C(O)=O
ALogP:3.265
Target:COX,Immunology & Inflammation related,Interleukins,NF-κB,NOS,TNF-alpha
Pathway:Immunology & Inflammation
Information:Madecassic acid (Brahmic acid), a natural triterpene first isolated from C. asiatica, has diverse anti-inflammatory and anti-diabetic effects, blocking NF-κB activation in macrophages and causing by iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 inhibition.
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