生物活性：Thalidomide-d4 is a deuterium labeled Thalidomide. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ~250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties[1][2].
IC50 & Target：Cereblon
分子量：262.25
Formula：C13H6D4N2O4
CAS 号：1219177-18-0
非标记 CAS：50-35-1
性状：固体
颜色：White to off-white
中文名称：沙利度胺 d4
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month