生物活性：Baclofen-d4 is the deuterium labeled Baclofen. Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research[1][2][3].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Baclofen-d4 相关抗体:
GABARAP Antibody
IP3 Receptor Antibody (YA1596)
GABA B Receptor 2 Antibody (YA1733)
GABA B Receptor 1 Antibody (YA2418)
GAD65 Antibody (YA758)
GABA A Receptor alpha 1 Antibody (YA1315)
GABA A Receptor beta 2 Antibody (YA1758)
GABA Transporter 1 Antibody (YA1795)
GAD67 Antibody (YA1807)
ABAT Antibody (YA1964)
GABA A Receptor alpha 5 Antibody (YA2249)
GABA A Receptor beta 1 Antibody (YA2261)
BGAT Antibody (YA2741)
GABARAPL2 Antibody (YA2882)
分子量：217.69
Formula：C10H8D4ClNO2
CAS 号：1189938-30-4
非标记 CAS：1134-47-0
性状：固体
颜色：White to off-white
中文名称：巴氯芬 d4
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month