生物活性：GW2580-d6 is the deuterium labeled GW2580. GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 μM. GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling[1].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
GW2580-d6 相关抗体:
M-CSF Antibody
CSF-1R Antibody (YA1299)
G-CSF Antibody (YA3307)
Destrin Antibody (YA1859)
DCI Antibody (YA2658)
DPS1 Antibody (YA2721)
M-CSF Receptor Antibody (YA3205)
G-CSF Receptor Antibody (YA3373)
分子量：372.45
Formula：C20H16D6N4O3
CAS 号：2733770-48-2
非标记 CAS：870483-87-7
性状：固体
颜色：White to off-white
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month