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「同位素标记抑制剂」O-Desmethyl Midostaurin-d5
生物活性:O-Desmethyl Midostaurin-d5 is a deuterium labeled O-Desmethyl PKC412. O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism[1].
IC50 & Target:IC50: active metabolite of Midostaurin[1]
分子量:561.64
Formula:C34H23D5N4O4
CAS 号:2699608-28-9
非标记 CAS:740816-86-8
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (528 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Levis M, et al. Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors. Blood. 2006 Nov 15;108(10):3477-83.
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