生物活性：Atorvastatin-d5 (hemicalcium) is the deuterium labeled Atorvastatin. Atorvastatin hemicalcium is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively[1][2][3].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Atorvastatin-d5 hemicalcium 相关抗体:
HMGCS2 Antibody
HMGB1 Antibody
HMGCR Antibody
Baf180 Antibody (YA1176)
BANF1 Antibody (YA1740)
LEF1 Antibody (YA3164)
HMGA1 Antibody (YA1185)
HMGA2 Antibody (YA1186)
Baf57 Antibody (YA2110)
HMGN2 Antibody (YA2839)
HMG4 Antibody (YA2992)
HMGB2 Antibody (YA2995)
HMGCL Antibody (YA3024)
分子量：583.71
Formula：C33H30D5FN2O5.1/2Ca
CAS 号：222412-82-0
非标记 CAS：134523-03-8
性状：固体
颜色：White to off-white
中文名称：阿托伐他汀 d5 (1/2钙盐)
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：4°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)