生物活性：Pirfenidone-d5 is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities[1][2][3].
IC50 & Target：TGF-β2[1][2]
CCL2 and CCL12[3]
分子量：190.25
Formula：C12H6D5NO
CAS 号：1020719-62-3
非标记 CAS：53179-13-8
性状：固体
颜色：White to light yellow
中文名称：吡非尼酮 d5
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month