生物活性：(R)-Praziquantel-d11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer[1].
IC50 & Target[1]：5-HT2B Receptor
Schistosome
Antischistosomal
体外研究(In Vitro)：(R)-Praziquantel ((R)-PZQ) is a G-protein-coupled receptor ligand. (R)-Praziquantel modulation of serotoninergic signaling occurs over a concentration range sufficient to regulate vascular tone of the mesenteric blood vessels where the adult parasites reside within their host. The important anthelmintic is supported by a broad, cross species polypharmacology with (R)-Praziquantel modulating signaling events in both host and parasite[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
(R)-Praziquantel-d11 相关抗体:
MTNR1A Antibody
分子量：323.47
Formula：C19H13D11N2O2
CAS 号：1399880-38-6
非标记 CAS：57452-98-9
性状：固体
颜色：White to off-white
中文名称：(R)-吡喹酮 d11
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month
纯度 & 产品资料
纯度： 99.57%
参考文献
[1]. Chan JD, et al. The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. Nat Commun. 2017 Dec 5;8(1):1910.
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