生物活性：Hydralazine-d4 hydrochloride is the deuterium labeled Hydralazine hydrochloride. Hydralazine hydrochloride is a direct-acting vasodilator that is used as an antihypertensive agent.
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Hydralazine-d4 hydrochloride 相关抗体:
HIF1 alpha Antibody
HIF1 beta Antibody
HIF 2 alpha Antibody
CA9 Antibody (YA1368)
HIF2 alpha Antibody (YA1445)
ORP150 Antibody (YA1478)
PHD3 Antibody (YA1612)
CITED2 Antibody (YA2596)
ORP1 Antibody (YA1477)
HIF1AN Antibody (YA1907)
OS9 Antibody (YA1939)
PHD2 Antibody (YA2431)
HIF Prolyl Hydroxylases Antibody (YA2975)
HLF Antibody (YA2990)
PHD1 Antibody (YA3325)
分子量：200.66
Formula：C8H5D4ClN4
CAS 号：2749234-32-8
非标记 CAS：304-20-1
中文名称：盐酸肼屈嗪-d4
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (525 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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[2]. Bourreli, B., et al., Additive effects of dihydralazine during enflurane or isoflurane hypotensive anaesthesia for spinal fusion. Can J Anaesth, 1988. 35(3 ( Pt 1)): p. 242-8.
 [Content Brief]
[3]. Kandler, M.R., et al., Hydralazine for essential hypertension. Cochrane Database Syst Rev, 2010(8): p. CD004934.
 [Content Brief]