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「同位素标记抑制剂」CAS:1216682-38-0|Lansoprazole sulfide-d4
生物活性:Lansoprazole sulfide-d4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 µM intracellularly and 0.46 µM in broth[1].
IC50 & Target:Proton pump[1]
IC50: 0.59 µM (Mycobacterium tuberculosis intracellularly), 0.46 µM (Mycobacterium tuberculosis in broth)[1]
分子量:357.39
Formula:C16H10D4F3N3OS
CAS 号:1216682-38-0
非标记 CAS:103577-40-8
性状:固体
颜色:White to off-white
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Powder:-20°C:3 years
In solvent:-80°C:6 months,-20°C:1 month
纯度 & 产品资料
纯度: ≥99.0%
参考文献
[1]. Mdanda S, et al. Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent. Biomed Chromatogr. 2017 Dec;31(12).
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