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「同位素标记抑制剂」CAS:2732985-25-8|Cinoxacin-d5
生物活性:Cinoxacin-d5 is the deuterium-labeled Cinoxacin (HY-B1085)[1]. Cinoxacin (Compound 64716),a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis[2][3].
IC50 & Target:MIC: 4-64 μg/mL (Gram-negative aerobic bacteria)[2]
体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量:267.25
Formula:C12H5D5N2O5
CAS 号:2732985-25-8
非标记 CAS:28657-80-9
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (542 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[Content Brief]
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