生物活性：Trabectedin D3 (Ecteinascidin 743 D3) is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has tje potential for soft tissue sarcoma and ovarian cancer treatment[1][2][3].
分子量：764.86
Formula：C39H40D3N3O11S
非标记 CAS：114899-77-3
性状：固体
颜色：Off-white to light yellow
中文名称：他比特啶 D3
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：-20°C, sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)