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「同位素标记抑制剂」Olaparib-d8
生物活性:Olaparib-d8 (AZD2281-d8) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator[1][2][3][4].
体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注。
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Olaparib-d8 相关抗体:
PARP1 Antibody
PARP2 Antibody
Cleaved PARP Antibody
Cleaved-PARP1 Antibody
PARP1 Antibody (YA245)
StAR Antibody
SSB Antibody (YA668)
GTF2H1 Antibody (YA1067)
BRAT1 Antibody (YA2294)
BRCC36 Antibody (YA2298)
Killin Antibody (YA3144)
分子量:442.51
Formula:C24H15D8FN4O3
非标记 CAS:763113-22-0
性状:固体
颜色:White to off-white
中文名称:奥拉帕尼 d8
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Powder:-20°C:3 years,4°C:2 years
In solvent:-80°C:6 months,-20°C:1 month
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