生物活性：Abemaciclib metabolite M2-d6 is the deuterium labeled Abemaciclib metabolite M2. Abemaciclib metabolite M2 (LSN2839567) is a metabolite of Abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s in the range of 1-3 nM. Anti-cancer activity[1][2].
体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Abemaciclib metabolite M2-d6 相关抗体:
Cyclin E1 Antibody (YA483)
CD133 Antibody
Cdk2 Antibody
Cdk4 Antibody
Cdk5 Antibody
Cdk6 Antibody
Cyclin D3 Antibody
Cdk7 Antibody
CDK16 Antibody
CDK5 Antibody (YA796)
CDK9 Antibody
CDKN2A/p16INK4a Antibody (YA508)
Phospho-CDK1 (Tyr15) Antibody
Phospho-CDK1/2/3 (Thr14) Antibody
Phospho-CDK2 (Tyr15) Antibody
Phospho-Cyclin B1 (Ser126) Antibody
CDKN2A/p16INK4a Antibody
CDKN2C Antibody
Phospho-CDC6 (Ser54) Antibody (YA1017)
Cyclin E2 Antibody (YA2594)
CDC25C Antibody (YA2624)
CDC6 Antibody (YA2626)
CDC40 Antibody (YA3168)
Cyclin A1/A2 Antibody (YA3336)
CRK Antibody (YA790)
Cyclin H Antibody (YA788)
Cyclin H Antibody
Phospho-CDC6 (Ser106) Antibody (YA1016)
CDC7 Antibody (YA1152)
Cyclin D3/CCND3 Antibody (YA1201)
分子量：484.58
Formula：C25H22D6F2N8
非标记 CAS：1231930-57-6
性状：固体
颜色：Off-white to light yellow
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：-20°C, sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)