生物活性：24-Methylenecholesterol-13C (Ostreasterol-13C) is the 13C labeled 24-Methylenecholesterol (HY-133968)[1]. 24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth[2][3][4].
体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
24-Methylenecholesterol-13C 相关抗体:
Catalase Antibody (YA552)
Catalase Antibody (YA811)
DGAT1 Antibody
C Reactive Protein Antibody (YA941)
PARK7/DJ1 Antibody (YA1799)
ACOX1 Antibody (YA1979)
C Reactive Protein Antibody (YA939)
C Reactive Protein Antibody (YA940)
ABHD5 Antibody (YA1108)
PON1 Antibody (YA1666)
PON2 Antibody (YA1688)
ACAT1 Antibody (YA1971)
分子量：399.66
Formula：C2713CH46O
非标记 CAS：474-63-5
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (544 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
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