Name:Canrenone
Synonyms:Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone
CAS Number:976-71-6
Formula:C22H28O3
M.w.:340.46
DMSO (mg/mL)Max Solubility:68
DMSO (mM)Max Solubility:199.73
Form:free base
SMILES:CC12CCC(=O)C=C1C=CC3C2CCC4(C)C3CCC45CCC(=O)O5
ALogP:3.519
Target:Mineralocorticoid Receptor
Pathway:Endocrinology & Hormones
Information:Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases.
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