Name:Quercetin Dihydrate
Synonyms:Sophoretin
CAS Number:6151-25-3
Formula:C15H10O7.2H2O
M.w.:338.27
DMSO (mg/mL)Max Solubility:67
DMSO (mM)Max Solubility:198.07
Form:Dihydrate
SMILES:O.O.OC1=CC(=C2C(=O)C(=C(OC2=C1)C3=CC=C(O)C(=C3)O)O)O
ALogP:1.216
Target:PI3K,Sirtuin
Pathway:PI3K/Akt/mTOR
Information:Quercetin (Sophoretin), a polyphenolic flavonoid found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine, is utilized in many different cultures for their nervous system and anticancer effects. Quercetin (dihydrate), a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively.
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