Name:Hypericin
Synonyms:Hyp, HY
CAS Number:548-04-9
Formula:C30H16O8
M.w.:504.44
DMSO (mg/mL)Max Solubility:100
DMSO (mM)Max Solubility:198.24
Form:free base
SMILES:CC1=C2C3=C(C)C=C(O)C4=C3C5=C6C2=C(C(=C1)O)C(=O)C7=C6C(=C(O)C=C7O)C8=C(O)C=C(O)C(=C58)C4=O
ALogP:5.04
Target:Hydroxylase,MAO,P450 (e.g. CYP17),PKC,Reverse Transcriptase,Telomerase
Pathway:Metabolism
Information:Hypericin (Hyp, HY) is a naturally occurring substance found in the common St. John's Wort (Hypericum species) with antidepressive, antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities. Hypericin has inhibitory effects on MAO (monoaminoxidase), PKC (protein kinase C), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450).
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